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This medication may cause drowsiness or dizziness. low blood pressure and worsening kidney function. Gynecomastia is usually reversible.

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Therefore, when spironolactone tablets and NSAIDs are used concomitantly, monitor closely to determine if the desired effect of the diuretic is obtained see Clinical Pharmacology 12.

Spironolactone and its metabolites what does spironolactone treat with radioimmunoassays for digoxin and increase the apparent exposure to digoxin. In some patients, the administration of an NSAID can reduce the diuretic, natriuretic, and antihypertensive effect of diuretics.

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-25 mg/day orally; may increase to 50 mg/day if needed; if 25 mg/day not tolerated, reduce to 25 mg every other day ACC/AHA guidelines recommend aldosterone antagonist to be added to an ACEI or ARB, plus a beta-blocker; patient conditions may also require additional medications e.

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What does spironolactone treat The recommended monitoring for potassium and creatinine is 1 week after initiation or what does spironolactone treat in dose of spironolactone, monthly for the first 3 months, then quarterly for what does spironolactone treat year, and then every 6 months. Caution is required in patients with a predisposition to metabolic or respiratory acidosis.

Caution is required in severely ill patients and those with relatively small urine volumes who are at greater risk of developing hyperkalaemia. Acidosis potentiates the hyperkalaemic effects of spironolactone and spironolactone may potentiate acidosis. Discontinue or interrupt treatment for serum potassium 5 mEq/L or for serum creatinine 4 mg/dL see section 4.


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