WebMD does not endorse any specific product, service, or treatment. Tolterodine (detrol) box 1 mg 10 amount of packaging.
"Bladder retraining". Retrieved 11 April 2020.
Tolterodine tartrate 4 mg beats/minute following administration of tolterodine 2 mg twice daily or 4 mg twice daily, respectively. eart rate increased by a mean of 2 or 6.
No data concerning the excretion of tolterodine into human milk are available. Consequently, Tolterodine Tartrate tablets is not recommended during pregnancy. There are no adequate data from the use tolterodine tartrate 4 mg tolterodine in pregnant women. The potential risk for humans is unknown. tudies in animals have shown reproductive toxicity see section 5.
Tolterodine tart er 4mg
Hours, respectively. Following single or multiple oral doses of tolterodine tartrate as conventional tablets the elimination half-life of the 5-hydroxymethyl metabolite in healthy tolterodine tart er 4mg is about 3. or 2.
2 The bladder wall muscle overactivity results in sporadic bladder muscle contraction, which increases pressure in the bladder and decreases the volume tolterodine l tartrate 4 mg urine the bladder can hold. 2 In addition, spontaneous bladder muscle contractions can lead to unexpected and frequent leakage of urine with symptoms of urinary urgency immediate urge to urinate frequency urinating more often than normal and incontinence loss of bladder control 2 Solifenacin is contraindicated for people with urinary retention, gastric retention, uncontrolled or poorly controlled closed-angle glaucoma, severe liver disease Child-Pugh tolterodine l tartrate 4 mg C 9 and hemodialysis.
2 With NDO, there is overactivity of the bladder wall muscle, which normally relaxes to allow storage of urine. 2 If NDO is not treated, increased pressure in the bladder can put the upper urinary tract at risk of harm, including possible permanent damage to the kidneys.Tolterodine product names goods:
- Breminal 1 mg
- Detrusitol 2 mg
- Tolorin 2 mg
- Toltem 2 mg
- Tolter 2 mg
- Tolterodin 1 mg
- Tolterodina 1 mg
- Toltérodine 1 mg
- Tolterodinum 2 mg
- Toltex 1 mg
- Ucol 1 mg
- Urginol 2 mg
- Uroflow 1 mg
- Urotrol 1 mg
Quinidine, procainamide or class III e. amiodarone, sotalol antiarrhythmic agents. These observations should be considered when use of tolterodine is contemplated in patients with a history of Tolterodine tartrate 4 mg interval prolongation or in patients receiving class IA e.
Tolterodine tart er 4mg cap
In addition, serum concentrations tolterodine tart er 4mg cap tolterodine were substantially higher and serum concentrations of the 5-hydroxymethyl metabolite were negligible in individuals with the poor-oxidizer phenotype compared with those observed in extensive metabolizers of the drug.
In pharmacokinetic studies, tolterodine was metabolized at a slower rate in poor metabolizers than in extensive metabolizers.
R 2-3% of patients receiving tolterodine 1 mg twice daily as conventional tablets, tolterodine tartrate 2 mg twice daily as conventional tablets, tolterodine tartrate 4 mg once daily as extended-release capsules, or placebo, respectively. Constipation tolterodine tartrate 4 mg reported in about. r 4-5% of patients receiving tolterodine tartrate 1 mg twice daily as conventional tablets, tolterodine tartrate 2 mg twice daily as conventional tablets, tolterodine tartrate 4 mg once daily as extended-release capsules, or placebo, respectively.
Dyspepsia, diarrhea, and weight gain also have been reported in patients receiving tolterodine. Abdominal pain has been reported in tolterodine tartrate 4 mg
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Reatment depends upon the cause of the nerve damage and resulting type of bladder control problem. Treatment options may include Kegel exercises, biofeedback, vaginal weight training, pelvic floor electrical stimulation, behavioral therapy, and medications. Such tolterodine tart er 4mg include urine retention, poor control of sphincter muscles, and tolterodine tart er 4mg bladder.
veractive bladder is a sudden involuntary contraction of the muscle wall of the bladder causing urinary urgency an immediate unstoppable need to urinate Overactive bladder is is a form of urinary incontinence.
Tolterodine l tartrate 4 mg Transition probabilities over 12 weeks were obtained from randomized trial data, and drug discontinuation rates were obtained from Quebec prescription claims data.
We compared 2 treatment strategies for the management of adult patients with UI: 1 generic oxybutynin with no further treatment for patients who discontinue and 2 generic oxybutynin with switch to tolterodine 2 mg BID for patients who discontinue.
Outcome measures were time in "normal" health state and quality-adjusted life-years QALYs using EuroQol-5D utility scores from a survey of Tolterodine l tartrate 4 mg patients with overactive bladder. Costs to the health care payer and patient out-of-pocket costs in Canadian dollars were included.
Use of tolterodine in patients with UI who discontinue initial therapy with generic oxybutynin lies within currently accepted benchmarks for cost-effectiveness.
We developed a 1-year Markov model 4-week cycle length with transitions between disease states of normal, mild, moderate, and severe.
|Respectively, versus 0.||However, overall differences in safety were not observed between geriatric and younger patients in phase III, controlled clinical studies of tolterodine tartrate 4 mg weeks' duration.||Tolterodine l tartrate 4 mg DETROL is a prescription medicine tolterodine l tartrate 4 mg adults used to treat the following symptoms due to a condition called overactive bladder: Urge urinary incontinence: a strong need to urinate with leaking or wetting accidents DETROL LA (tolterodine tartrate extended release capsules) did not help the symptoms of overactive bladder when studied in children.|
|Tolterodine tartrate 4 mg tolterodine acid) were approximately 10- to 30-fold higher in these patients than in healthy individuals. Serum concentrations of other metabolites (e.||Beats/minute and 6.||Tolterodine tartrate 4 mg The primary metabolic route involves the oxidation of the 5-methyl group and is mediated by the cytochrome P450 2D6 (CYP2D6) and leads to the formation of a pharmacologically active metabolite, 5-HMT. Tolterodine is extensively metabolized by the liver following oral dosing.|
|Take DETROL LA capsules once a day with liquid. Do not change your dose unless told to do so by your doctor.||Tolterodine l tartrate 4 mg Oral bioavailability of conventional tolterodine tartrate tablets may be increased (e. Peak and trough serum tolterodine concentrations achieved with extended-release capsules are approximately 75 and 150% respectively, of those achieved with conventional tablets.||Tolterodine tartrate 4 mg The child fully recovered. A 27-month-old child who ingested 5 to 7 tolterodine immediate release tolterodine tartrate 4 mg mg tablets was treated with a suspension of activated charcoal and was hospitalized overnight with symptoms of dry mouth.|
Tolterodine tart er 4mg cap of placebo treated patients. of patients treated with Tolterodine Tartrate tablets and in 7. confusion, disorientation, delusion have been reported after tolterodine therapy was initiated in patients taking cholinesterase inhibitors for the treatment of dementia. Headaches were also reported very commonly and occurred in 10. The most commonly reported adverse reaction was dry mouth, which occurred in 35% of patients treated with Tolterodine Tartrate tablets and in 10% of placebo treated patients.
Dyspepsia, constipation, abdominal pain, flatulence, vomiting, diarrhoea Cases of aggravation of symptoms of dementia e.
10. die Zulassung organischer Peroxide zur Beförderung in Großpackmitteln (IBC ) nach Absatz 184.108.40.206.2 und die Festlegung von Bedingungen ...:
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Overall, extended release preparations had less risk of dry mouth tolterodine l tartrate 4 mg two tolterodine l tartrate 4 mg 12 weeks. One extended release preparation versus another: there was less risk of dry mouth with oral extended release tolterodine than oxybutynin RR.
Extended versus immediate release preparations of oxybutynin or tolterodine, or both: there were no statistically significant differences for cure or improvement, leakage episodes or micturitions in 24 hours or withdrawals due to adverse events, but there were few data.
- Tolterodine synonym: breminal, detrusitol, tolorin, toltem, tolter, tolterodin, tolterodina, toltérodine, tolterodinum, toltex, ucol, urginol, uroflow, urotrol
- Active substances: detrol
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Do not crush, chew, break, or open a controlled-release capsule. Your doctor may occasionally change your dose to make sure you get the best results. Take exactly as prescribed by your doctor. o not take in larger or smaller amounts tolterodine tart er 4mg for longer than recommended. o not use this medication without telling your doctor if you are breast-feeding a baby.
ollow the directions on your prescription tolterodine tart er 4mg
5-HMT, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. Both tolterodine and 5-HMT exhibit a high specificity tolterodine tartrate 4 mg muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels.
After oral administration, tolterodine is metabolized in the liver, resulting in the formation of 5-hydroxymethyl tolterodine 5-HMT the major pharmacologically active metabolite. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. tolterodine tartrate 4 mg
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Terms and conditions
What is tolterodine used for?
DETROL LA treats the symptoms of overactive bladder leaks, strong sudden urges to go, going too often This Savings Offer is not valid when the entire cost of your prescription drug is eligible to tolterodine tartrate 4 mg reimbursed by your private tolterodine tartrate 4 mg plans or other health or pharmacy benefit programs You must deduct the savings received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf Patients who are enrolled in Medicare, Medicaid, or another state or federal healthcare program may use this Savings Offer if paying for the prescription covered by this Savings Offer outside of their government insurance benefit, and no claim is submitted to Medicare, Medicaid, or any federal or state healthcare program.
There may be other options. Ask your doctor if DETROL LA is right for you.
Can tolterodine affect my period?
Extended-release tolterodine tolterodine tartrate 4 mg also appears to be more effective than placebo in relieving urinary symptoms e. However, in one 4-week study in which cystometry was used to evaluate outcomes, only the 2-mg dosage was more effective than placebo tolterodine tartrate 4 mg increasing the volume at first contraction and the maximum cystometric capacity, although both dosages increased the residual volume compared with placebo.
urinary frequency, urgency, urge incontinence in patients with overactive bladder. In addition, in several studies, patients' perceptions concerning improvement of symptoms also were substantially greater using the higher dosage of tolterodine.
Is tolterodine otc?
Or 49-56% of patients receiving tolterodine tartrate 1 mg twice daily as conventional tablets, tolterodine tartrate 2 mg twice daily as conventional tablets, tolterodine tartrate 4 mg once daily as extended-release capsules, or placebo, respectively. In therapeutic dosages, tolterodine tartrate generally is well tolerated. Most adverse effects of tolterodine were mild to moderate.
In placebo-controlled, phase III clinical studies of 12 weeks' duration, adverse effects were reported in.
What are tolterodine tartrate tablets for?
A nerve problem might affect your bladder control if the nerves that are supposed to carry messages between the brain and the bladder do not work properly. Such problems include urine retention, poor control of sphincter tolterodine tartrate 4 mg, and overactive bladder. When this happens, the condition is called urge incontinence or overactive bladder.
What is this for tolterodine tartrate?
Clearance of oral tolterodine administered as conventional tolterodine tartrate tablets was about 17 or 95 mL/minute per kg in patients tolterodine l tartrate 4 mg liver cirrhosis or healthy individuals, respectively. In those with poor-oxidizer phenotype, less than 2.
of the dose was excreted as unchanged tolterodine and less than 1% as the 5-hydroxymethyl metabolite. In healthy men with the extensive-oxidizer phenotype, apparent oral clearance of tolterodine is about 8900 or 6917 mL/minute following single 4 mg or multiple 4 mg twice daily oral doses of the drug administered as conventional tolterodine l tartrate 4 mg respectively, while in healthy men with the poor-oxidizer phenotype, apparent oral clearance of tolterodine under the same conditions reportedly is about 283 or 183 mL/minute, respectively.
Can i take 8mg of tolterodine?
No differences in the safety profile tolterodine tartrate 4 mg tolterodine were identified bid in 986 patients and to placebo in 683 patients exposed for 12 weeks in five Phase 3, controlled clinical studies. Read the entire detailed patient monograph for Detrol Tolterodine Tartrate he Phase 2 and 3 clinical trial program for DETROL Tablets months.
Can tolterodine affect birth control?
4 It is taken by mouth. 3 Benefits appear similar to other medications in the class.
What is the least expensive drug similar to tolterodine?
CI 1. 3 to 1. 1, data from three trials patient reported cure or improvement RR. 3 to -0.
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Exposure levels of other metabolites of tolterodine acid, N-dealkylated tolterodine and N-dealkylated hydroxy tolterodine) were significantly volunteers. In a study conducted in patients with creatinine clearance between 10 and 30 mL/min, tolterodine and impairment than in healthy volunteers. ...
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